Manuel R. Mercier

Google Scholar Profile

My general scientific interest is to understand the orchestration of neuronal integration processes with a specific interest in neuronal oscillations. To this aim, I am studying the influence of cognitive functions (attention, memory … ) on multisensory interactions using psychophysics and electrophysiological approaches in human.

Short Bio:

I was originally trained in neurophysiology at University Paris XI Orsay. After obtaining the Master in Cognitive Sciences of Paris in 2003, I completed my PhD at Ecole Polytechnique de Lausanne (Switzerland) in 2009, supervised by Prof. Olaf Blanke. My thesis examined visual processing using EEG and clinical approaches in collaboration with Christoph Michel at the Geneva University Hopsital. I then worked as a post-doctoral research fellow with Prof. John Foxe and Sophie Molholm at the Albert Einstein College of Medicine (New York, USA). There I studied the role of neuronal oscillations on multisensory integration using ECoG and EEG. Next, I worked with Fred Lado and  Ashesh Mehta to develop multimodal tools  for human intracranial investigations (electrophysiology, electrical stimulatiion, fMRI, TEP). Thanks to David Groppe, this collaborative framework is being materialized through the ongoing release of an open toolbox for localizing and visualizing human intracranial data.

Publications:
  1. Mercier MR, Bickel S, Megevand P, Groppe DM, Schroeder CE, Mehta AD, Lado FA (2016) Evaluation of cortical Local Field Potential diffusion in Stereotactic Electro-EncephaloGraphy recordings: a glimpse on white matter signal. Neuroimage 147:219-232
  2. Mercier MR, Schwartz S, Spinelli L, Michel CM, Blanke O (2016) Dorsal and ventral stream contributions to form-from-motion perception in a patient with form-from motion deficit: a case report. Brain Structure and Function (In Press)
  3. Groppe DM, Bickel S, Dykstra AR, Wang X, Megevand P, Mercier MR, Lado FA, Mehta AD, Honey CJ (2016) iELVis: An open source MATLAB toolbox for localizing and visualizing human intracranial electrode data. bioRxiv 069179
  4. Mercier MR, Molholm S, Fiebelkorn IC, Butler JS, Schwartz TH, Foxe JJ (2015) Neuro-oscillatory phase alignment drives speeded multisensory response times: an electro-corticographic investigation. J Neurosci 35:8546-57
  5. Andrade GN, Butler JS, Mercier MR, Molholm S, Foxe JJ (2015) Spatio-temporal dynamics of adaptation in the visual system: A high-density electrical mapping study. Eur J Neurosci 41:925-39
  6. Molholm S, Mercier MR, Liebenthal E, Schwartz TH, Ritter W, Foxe JJ, De Sanctis P (2014) Mapping phonemic processing zones along human perisylvian cortex: an electro-corticographic investigation. Brain, Structure and Function  219(4):1369-83
  7. Altschuler TS, Molholm S, Butler JS, Mercier MR, Brandwein AB, Foxe JJ (2014) The effort to close the gap: Tracking the development of illusory contour from childhood to adulthood with high-density electrical mapping. Neuroimage 90: 360-73
  8. Thirioux B, Mercier MR, Blanke O, Berthoz A (2014) The cognitive and neural time course of empathy and sympathy: an electrical neuroimaging study on self-other interaction. Neuroscience. 16;267:286-306
  9. Bahramisharif A, vanGerven MAJ, Aarnoutse EJ, Mercier MR, Schwartz TH, Foxe JJ, Ramsey NF, Jensen O (2013) Propagating neocortical gamma bursts are coordinated by traveling alpha waves. J Neurosci 33:18849-54
  10. Mercier MR, Foxe JJ, Fiebelkorn IC, Butler JS, Schwartz TH, Molholm S (2013). Auditory-driven phase reset in visual cortex: Human electrocorticography reveals mechanisms of early multisensory integration. Neuroimage 79:19-29.
  11. Fiebelkorn IC, Snyder AC, Mercier MR, Butler JS, Molholm S, Foxe JJ (2013) Cortical cross-frequency coupling predicts perceptual outcomes. Neuroimage 69:126-137.
  12. Butler JS, Foxe JJ, Fiebelkorn IC, Mercier MR, Molholm S (2012) Multisensory representation of frequency across audition and touch: high density electrical mapping reveals early sensory-perceptual coupling. J Neurosci 32:15338-44.
  13. Lopez C, Mercier MR, Halje P, Blanke O (2011) Spatiotemporal dynamics of visual vertical judgments: early and late brain mechanisms as revealed by high-density electrical neuroimaging. Neuroscience 181:134-149.
  14. Fiebelkorn IC, Foxe JJ, Butler JS, Mercier MR, Snyder AC, Molholm S (2011) Ready, set, reset: stimulus-locked periodicity in behavioral performance demonstrates the consequences of cross-sensory phase reset. J Neurosci 31:9971-81.
  15. Butler JS, Molholm S, Fiebelkorn IC, Mercier MR, Schwartz TH, Foxe JJ (2011) Common or redundant neural circuits for duration processing across audition and touch. J Neurosci 31:3400-06.
  16. Thirioux B, Mercier MR, Jorland G, Berthoz A, Blanke O (2010) Mental imagery of self-location during spontaneous and active self-other interactions: an electrical neuroimaging study. J Neurosci 30:7202-14.
  17. Plomp G, Mercier MR, Otto TU, Blanke O, Herzog MH (2009) Non-retinotopic feature integration decreases response-locked brain activity as revealed by electrical neuroimaging. Neuroimage 48:405-414.
  18. Mercier M, Schwartz S, Michel CM, Blanke O (2009) Motion direction tuning in human visual cortex. Eur J Neurosci 29:424-434.
  19. Dieguez S, Mercier MR, Newby N, Blanke O (2009) Feeling numbness for someone else's finger. Curr Biol 19:R1108-1109.
  20. Lopez C, Bachofner C, Mercier M, Blanke O (2009) Gravity and observer's body orientation influence the visual perception of human body postures. J Vis 9:1 1-14.
  21. Morel S, Ponz A, Mercier M, Vuilleumier P, George N (2009) EEG-MEG evidence for early differential repetition effects for fearful, happy and neutral faces. Brain Res 1254:84-98.
  22. Blanke O, Brooks A, Mercier M, Spinelli L, Adriani M, Lavanchy L, Safran AB, Landis T (2007) Distinct mechanisms of form-from-motion perception in human extrastriate cortex. Neuropsychologia 45:644-653.