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contact: jean-michel.hupe at
cerco.ups-tlse . fr
phone: +33 (0)5 6274 6124
postal address: CNRS CERCO UMR 5549, Pavillon
Baudot, CHU Purpan, BP 25202, 31052 Toulouse Cedex
My research is focused on
visual perception, with more and
more emphasis on its subjective
For the full list of my publications and downloadable pdf files, please
I did my Ph.D. thesis (1995-1999) in Lyon (France) with Jean
Bullier on the role of feedback connections in motion perception. Then
I spent three years at New York University working with Nava Rubin on
motion perception using psychophysics methods and learning fMRI. I
started to work on the bistable perception of ambiguous stimuli (see my
which is still accessible). I came back to France in 2002, in
Toulouse's CerCo lab, where I was recruited in 2004 as a CNRS research
I have been working on three research projets, while trying to improve on methodological issues.
mostly in vision using plaid stimuli (demo),
but also in audition thanks to
the collaboration with Daniel
These are my two most representative publications in this field:
Hupé, J.-M., Rubin, N., 2003. The dynamics of bi-stable alternation
ambiguous motion displays: a fresh look at plaids. Vision Research 43,
531 - 548.
Pressnitzer, D., Hupé, J.-M., 2006. Temporal dynamics of auditory and
visual bistability reveal common principles of perceptual organization.
Current Biology 16, 1351-1357.
I am currently working on the dynamics of tristable
perception. A paper just got published on this subject:
Pressnitzer, D. 2012. The initial phase of auditory and visual scene analysis. Phil Trans R Soc B 367, 942-953. <link> Send me an e-mail to receive the pdf.
This article belongs to a special issue of the Philosophical Transactions of the Royal Society B: Biological Sciences:
Issue 'Multistability in perception: binding sensory modalities'
compiled and edited by Jean-Luc Schwartz, Nicolas Grimault, Jean-Michel
Hupé, Brian C. J. Moore and Daniel Pressnitzer: 5 April 2012; Vol. 367,
No. 1591. The Table of Contents is available here.
Meanwhile, I'm feeding John
Rinzel and his postdoc Gemma Huguet at NYU with data so they
can come up with nice theoretical explanations of what's going on.
since 2006 and in collaboration with Michel Dojat.
We studied grapheme color synesthesia extensively using
phenomenological reports, psychophysics, functional and structural MRI.
The Neural Bases of Grapheme-Color Synesthesia Are
Not Localized in Real Color-Sensitive Areas (2012)See also the
Jean-Michel Hupé; Cécile Bordier; Michel Dojat
Cerebral Cortex, 22, 1622:1633.
links Abstract, Full
Synesthésie, expression subjective d’un palimpseste neuronal ? (2012)
médecine/sciences, 28(8-9), 765-771. pdf
Ruiz is currently doing his PhD project in Grenoble with
Michel Dojat and myself.
This is my latest research interest, triggered by the diversity of
subjective reports gathered when working on synesthesia. The
observation is simple: we do not think the same way, especially when
dealing with so-called "mental images". The challenge is: how can we
get an objective measure of this diversity of subjective experiences?
(4) Methodological developments.
In my papers, I tried to promote a rigorous usage of
statistical tests, and to propose alternatives when validity conditions
were not met.
- In single-unit electrophysiology, I proposed to use bootstrap and randomization tests (Hupé et al 1998, 2001a,b).
For the analysis of response times, in particular in multistable
perception, the Log transformation of the data is in most cases
mandatory. cf Hupé & Rubin 2003, as well as
weak effects or correlations mean nothing. see Hupé JM, Lamirel C,
Lorenceau J. Pupil dynamics during bistable motion perception. J Vis
2009; 9: 1-19. <link>
Effect sizes should be always reported (Partial eta square seems the good choice).
fMRI analysis, I criticized the confusion between "a priori" and
'hypothesis", leading to the propagation of false positive results. I
also proposed an index to measure the reproducibility of results. See
Hupé et al. 2011, Cerebral Cortex.
I'm also interested in
oculomotor signals, in particular as a potential source of artefacts.
In 2009, we showed pupil responses to button presses and blinks. We
also measured the consequences of blinking on the BOLD signal measures
with fMRI. We suggest that fMRI researchers should no longer ignore the
existence of blinks:
Hupé J-M, Bordier C, Dojat M. A BOLD signature of eyeblinks in the visual cortex. Neuroimage 2012; 61: 149–61.<link>
Psychophysics, eyetracking, fMRI
PRESENT, ACTIVE COLLABORATIONS
Michel Dojat, Grenoble Institut des Neurosciences
Daniel Pressnitzer, LPP & DEC, Paris.
John Rinzel, Center for Neural Science, New York University
Team at CerCo
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