DMS48






bb The DMS48 is a test of visual recognition memory test designed for the assessment of early Alzheimer’s disease. The hypotheses underlying the development of the DMS48 can be found in the first paragraphs of the original article in Neurology (Barbeau et al, 2004). Similar ideas were fully developped in a recent opinion paper (Didic et al, 2011). 

Downloading the DMS48

bb The DMS48 can be downloaded and used freely.

 
bb Downloading (you will need Set 1, Set 2 and the recording sheets, Set 3 is optional)

- Set 1

- Set 2

- Set 3

- Recording sheets


bb Instructions and normalization of this test were published in Barbeau E, Tramoni E, Joubert S, Mancini J, Ceccaldi M, Poncet M. (2004). Évaluation de la mémoire de reconnaissance visuelle : normalisation d’une nouvelle épreuve en choix forcé et utilité en neuropsychologie clinique. In Van-der-Linden M et Gremem (Eds). L'évaluation des troubles de la mémoire. Présentation de quatre tests de mémoire épisodique (avec leur étalonnage). Marseille, éditions Solal. p 85-101. The norms were acquired in French subjects.

bb A shorten English version of the instructions and norms can be found here .


Research articles on the DMS48


De Anna F, Didic M, Barbeau EJ, Mancini J, Felician O, Ceccaldi M. (2014). Increasing cognitive changes during follow-up in amnestic Mild Cognitive Impairment patients with impaired visual recognition memory. Neuropsychology, 28(1): 98-105.

Didic M, Felician O, Barbeau EJ, Mancini J, Latger-Florence C, Poncet M, Ceccaldi M. (2013). Impaired visual recognition memory predicts Alzheimer’s disease in amnestic MCI. Dementia and Geriatric Cognitive Disorders, 35, 291-299.

Didic M, Barbeau EJ, Felician O, Tramoni E, Guedj E, Poncet M, Ceccaldi M. (2011). Which memory system is impaired first in AD? Journal of Alzheimer's disease, 27(1), 11-22.

Didic-Hamel Cooke M, Ranjeva JP, Barbeau EJ, Confort-Gouny S, Le Fur Y, Felician O, Poncet M, Ceccaldi M, Cozzone PJ. (2010). Impaired visual recognition memory in amnestic MCI is associated with subhippocampal metabolic changes on MRSI. Journal of Alzheimer's disease, 22(4), 1268-1279.
PDF Barbeau EJ, Ranjeva PJ, Didic M, Confort-Gouny S, Felician O, Soulier E, Cozzone P, Ceccaldi M, Poncet M. (2008) Grey matter loss in amnestic MCI patients according to their profile of memory impairment. Neuropsychologia, 46, 1009-1019.

Guedj E, Barbeau E, Didic M, Felician O, de Laforte C, Ceccaldi M, Mundler O, Poncet M. (2006). Identification of subgroups in amnestic Mild Cognitive Impairment. Neurology, 67, 356–358.

Barbeau E, Didic M, Tramoni E, Felician O, Joubert S, Sontheimer A, Ceccaldi M, Poncet M. (2004). Evaluation of visual recognition memory in MCI patients. Neurology, 62, 1317-1322.


Some other studies in which the DMS48 was used



Barbeau EJ, Pariente J, Felician O, Puel M. (2011). Visual recognition memory: a double anatomo-functional dissociation. Hippocampus, 21(9), 929-934.

PDF

Barbeau EJ, Didic M, Felician O, Tramoni E, Guedj E, Ceccaldi M, Poncet M. (2006). Pure progressive amnesia: An atypical amnestic syndrome? Cognitive Neuropsychology, 23(8), 1230–1247.


Book chapters on the DMS48 (available on request)

bb Barbeau EJ, Ceccaldi M. (2010). L’évaluation des troubles de la mémoire au stade prédémentiel de la maladie d’Alzheimer : le DMS48. Neurologie.com, 2(6), 1-3.

bb Barbeau EJ, Guedj E, Felician O, Didic M, Ranjeva JP, Poncet M and Ceccaldi M. (2007). Assessing memory impairment in early Alzheimer’s disease: the DMS48. In Vellas B, Grundman M, Feldman H, Fitten LJ, Winblad B, Giacobini E (Eds). Research and Practice in Alzheimer's Disease and Other Dementias. Vol. 12. Paris, Serdi Publisher. p 134-138.

bb Barbeau E, Felician O, Joubert S, Didic M, Poncet M, Ceccaldi M. (2006). Test de reconnaissance d'images et maladie d'Alzheimer. In Michel BF, Verdureau F, Dubois B (Eds). Images et démences. Monographie du Groupe de Recherche sur la Maladie d’Alzheimer. Marseille, éditions Solal. p 171-180.

bb Barbeau E, Tramoni E, Joubert S, Mancini J, Ceccaldi M, Poncet M. (2004). Évaluation de la mémoire de reconnaissance visuelle : normalisation d’une nouvelle épreuve en choix forcé et utilité en neuropsychologie clinique. In Ergis AM, Gely-Nargeot MC, Van-der-Linden M (Eds) Les troubles de la mémoire dans la maladie d'Alzheimer. Marseille, éditions Solal. p 85-101.


Acknowledgements

These studies are carried out in collaboration with the Service de Neurologie et de Neuropsychologie (Mira Didic, Olivier Felician, Mathieu Ceccaldi and Michel Poncet); Service Central de Biophysique et de Médecine Nucléaire (Eric Guedj) and CRMBM CNRS UMR 6612 (Jean-Philippe Ranjeva and Patrick Cozzone), AP-HM Timone, Marseille, France. They are supported by PHRC AP-HM 2001/54 and France Alzheimer.

Contact

emmanuel.barbeau "at" cerco.ups-tlse.fr
Personal page
Centre de Recherche Cerveau et Cognition (CERCO)
UMR 5549 (CNRS-UPS)
Faculté de Médecine de Rangueil
31062 Toulouse Cedex 9
France